MI Paste is the only product for professional use containing the active ingredient RECALDENT™ (CPP-ACP), a special milk-derived phosphopeptide that binds calcium and phosphate to tooth surfaces, plaque and surrounding soft tissue. MI Paste is a water-based, sugar-free créme that is applied directly to the tooth surface or oral cavity. MI Paste with RECALDENT™ (CPP-ACP) restores the oral mineral imbalances that cause demineralization by replacing minerals while improving saliva flow and fluoride uptake as well as soothing sensitive surfaces - making it an ideal treatment for:
- Reversing tooth sensitivity and restoring enamel gloss after whitening procedures
- Relieving dry mouth caused by certain medications
- Reducing high oral acid levels from excessive soft drink consumption
- Reversing tooth sensitivity before and after professional cleaning
- Reducing high oral acid levels - sometimes a consequence of pregnancy
- Buffering acids produced by bacteria and plaque
- Regular conditioning during orthodontics, during and after bands or brackets have been removed, to prevent and reverse white spot lesions
- Providing a topical coating for patients suffering from erosion, caries and conditions arising from xerostomia
Use MI Paste™
- After tooth whitening
- For pregnant women
- For children six years and under
- During and/or after orthodontics
- For desensitizing
- To provide extra protection for teeth
MI Paste is pleasant tasting, and can be applied directly with a clean finger onto the teeth, smeared over all surfaces and left in place to slowly dissolve overnight. Any material that is swallowed is completely safe, and will contribute towards dietary calcium.
The Science behind MI Paste:
MI Paste releases RecaldentTM (CPP-ACP) which adheres to soft tissue, plaque, pellicle and hydroxyapatite delivering amorphous calcium and phosphate into the saliva and plaque fluid. The mechanism of action is similar to that of the salivary protein statherin and the supply of bioavailable calcium and phosphate is able to drive remineralization, buffer acid and reduce the plaque acid effect on tooth structure. An analysis of the chemistry of demineralization and remineralization indicates that a major source of mineral oss in the caries process is the destruction of apatite with the creation of water as a by-product, and the leakage of a neutral species calcium hydrogen phosphate across a porous enamel surface.
When placed on the surface of a tooth, RecaldentTM (CPP-ACP) interacts with hydrogen ions and forms the same species calcium hydrogen phosphate which, under a diffusion gradient, can enter into the tooth, react with and
consume the water to produce enamel mineral, thereby removing subsurface mineral defects.
MI Paste treatment of enamel subsurface caries has been shown to cause rapid remineralization, and this causes a change in the appearance of the lesions. Any incipient white spot lesions which are developing because of cariogenic plaque can be treated locally with RecaldentTM (CPP-ACP) to achieve subsurface remineralization. This will occur in fairly short periods of time – in the order of two to four weeks.
A key principle with RecaldentTM (CPP-ACP) is that the longer the material is maintained in the mouth, the more effective the result. MI Paste, which is the recommended homecare form of the product, contains 10% of the RecaldentTM (CPP-ACP) molecule by weight.



